JC-1 (CBIC2) (solution) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585 nm, Em=590 nm) , When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=510 nm, em= 527 nm) [1].Solvent and concentration: DMSO: 1.5 mM
Molecular Weight:
652.22
CAS Number:
[3520-43-2]
Formula:
C25H27Cl4IN4
Target:
Fluorescent Dye
Application Notes:
MCE Product type: Dye Reagents
* VAT and and shipping costs not included. Errors and price changes excepted
