Deoxycytidine Kinase, Human (EC 2.7.1.74) is a rate-limiting enzyme in the de novo pathway. Deoxycytidine Kinase, Human captures extracellular deoxyribonucleosides for use in intracellular deoxyribonucleotide metabolism. Deoxycytidine Kinase, Human functions as a dimer in cells to phosphorylate deoxycytidine as its major substrate as well as deoxyadenosine and deoxyguanosine and can activate various nucleoside analogue therapeutics[1].
Target:
Endogenous Metabolite
Application Notes:
Enzyme
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