EGFR C797S/L858R Recombinant Human Active Protein Kinase Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-E70696
Supplier Catalog Number:
HY-E70696
Alternative Catalog Number:
MCE-HY-E70696-1UNIT
Manufacturer:
MedchemExpress
Category:
Proteine/Peptide
EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR C797S/L858R Recombinant Human Active Protein Kinase is a recombinant EGFR C797S/L858R protein that can be used to study EGFR C797S/L858R-related functions[1].
Target:
EGFR
Application Notes:
MCE Product type: Enzyme
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