Omeprazole sulfone-13C,d3, CAS [[1261393-28-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-G0007S1
Supplier Catalog Number:
HY-G0007S1
Alternative Catalog Number:
MCE-HY-G0007S1-5MG,MCE-HY-G0007S1-1MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
Omeprazole sulphone-13C,d3
Omeprazole sulfone-13C,d3 is the deuterium and 13C labeled Omeprazole sulfone. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair[1][2][3].
