N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a delta-opioid agonist[1][2].
Molecular Weight:
312.80
Purity:
98.99
CAS Number:
[6104-71-8]
Formula:
C17H17ClN4
Target:
Drug Metabolite,mAChR,Opioid Receptor,Virus Protease
Application Notes:
MCE Product type: Reference compound
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