N-Desmethylclozapine-d8 (hydrochloride) is the deuterium labeled N-Desmethylclozapine hydrochloride. N-Desmethylclozapine hydrochloride is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine hydrochloride is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine hydrochloride is also a delta-opioid agonist[1][2][3].
Molecular Weight:
357.31
Purity:
99.74
CAS Number:
[2705402-91-9]
Formula:
C17H10D8Cl2N4
Target:
Drug Metabolite,mAChR,Opioid Receptor,Virus Protease
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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