Regorafenib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRbeta, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.
Molecular Weight:
498.81
Purity:
99.32
CAS Number:
[835621-11-9]
Formula:
C21H15ClF4N4O4
Target:
Drug Metabolite,PDGFR
Application Notes:
MCE Product type: Reference compound
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