MCE Polymyxin B (1,000*), Sterile (50 mg/mL) is a filtered and sterilized antibiotic solution that can be used directly in cell culture. Polymixin B is a mixture of B1 and B2 polypeptides obtained from different strains of Bacillus polymyxa, with antibacterial activity against gram-negative bacteria. It can bind lipopolysaccharide (LPS) of the outer membrane of gram-negative bacteria and disrupts the cytoplasmic membrane by inducing large pores to allow nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane.
Application Notes:
MCE Product type: Kits
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