Human iPSC/ESC Cortical Brain Organoid Induction Differentiation Kit

Catalog Number: MCE-HY-K6301
Article Name: Human iPSC/ESC Cortical Brain Organoid Induction Differentiation Kit
Biozol Catalog Number: MCE-HY-K6301
Supplier Catalog Number: HY-K6301
Alternative Catalog Number: MCE-HY-K6301-1KIT
Manufacturer: MedchemExpress
Category: Kits/Assays
MCE Human iPSC/ESC Cortical Brain Organoid Induction Differentiation Kit is a standardized culture system specifically designed to recapitulate the developmental processes and functional features of the human cerebral cortex through forebrain ventralization-based signaling regulation. By sequentially activating the Wnt/beta-catenin pathway and gradually inhibiting BMP/Smad signaling, this system efficiently drives human pluripotent stem cells (PSC) to differentiate into high-purity glutamatergic neurons (VGLUT1/2+ > 85%), while simultaneously promoting the formation of Pax6+/BLBP+ radial glial cells that establish a biomimetic ventricular-zone-like structure.
Application Notes: MCE Product type: Kits