Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 µM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 µM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 µM) and D4 (EC50=2 µM) receptor.
Molecular Weight:
295.38
Purity:
99.90
CAS Number:
[475-83-2]
Formula:
C19H21NO2
Target:
5-HT Receptor,Dopamine Receptor,Parasite
Application Notes:
MCE Product type: Natural Products
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