Cyclovirobuxine D (CVB-D) is the main active component of the traditional Chinese medicine Buxus microphylla. Cyclovirobuxine D induces autophagy and attenuates the phosphorylation of Akt and mTOR[1]. Cyclovirobuxine D inhibits cell proliferation of gastric cancer cells through suppression of cell cycle progression and inducement of mitochondria-mediated apoptosis[2]. Cyclovirobuxine D is beneficial for heart failure induced by myocardial infarction[3].
Molecular Weight:
402.66
Purity:
99.70
CAS Number:
[860-79-7]
Formula:
C26H46N2O
Target:
Akt,Apoptosis,Autophagy,mTOR
Application Notes:
MCE Product type: Natural Products
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