Phloretin (NSC 407292, RJC 02792) is a flavonoid extracted from Malus pumila Mill., has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC50values of 49 µM and 61 µM, respectively[1].Phloretin has the potential for the treatment of rheumatoid arthritis (RA) and allergic airway inflammation[4].
Molecular Weight:
274.27
Purity:
99.92
CAS Number:
[60-82-2]
Formula:
C15H14O5
Target:
Endogenous Metabolite,GLUT,SGLT
Application Notes:
MCE Product type: Natural Products
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