(Rac)-Hesperetin is the racemate of Hesperetin (HY-N0168), an orally active multi-target inhibitor. (Rac)-Hesperetin exhibits significant anti-tumor and anti-inflammatory activities by blocking the TGF-beta1-mediated Fyn/RhoA signaling axis and the TLR4-MyD88-NF-kappaB inflammatory pathway. (Rac)-Hesperetin inhibits the formation of actin stress fibers and the migration and invasion of cancer cells, and is suitable for triple-negative breast cancer research. In inflammation models, (Rac)-Hesperetin effectively alleviates lung injury by reducing the release of pro-inflammatory mediators and regulating the activity of oxidative stress enzymes, and is suitable for acute lung injury research. (Rac)-Hesperetin also interferes with the entry and early replication processes of channel catfish virus, inhibits viral gene expression and progeny virus production, thereby protecting cells from virus-induced cytopathic effects[1][2][3].
Molecular Weight:
302.28
Purity:
99.28
CAS Number:
[69097-99-0]
Formula:
C16H14O6
Target:
NF-kappaB,TGF-beta/Smad
Application Notes:
MCE Product type: Natural Products
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