(Rac)-Hesperetin is the racemate of Hesperetin. Hesperetin is a natural flavanone that can be found in citrus, and acts as a potent and orally active broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation. Hesperetin displays a range of bioactivities including antioxidant, anti-inflammatory, and anti-cancer. Hesperetin is found to induce cell-cycle arrest at G2/M phase. Hesperetin can reduce Bcl-2 and enhance BaxM. Hesperetin induces apoptosis through inhibiting NF-kappaB receptor[1][2][3][4].
Molecular Weight:
302.28
Purity:
99.28
CAS Number:
[69097-99-0]
Formula:
C16H14O6
Target:
Apoptosis,Autophagy,Bcl-2 Family,NF-kappaB,p38 MAPK,Reactive Oxygen Species (ROS)
Application Notes:
Natural Products
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