Benzoylmesaconine is a monoester-type alkaloid and is the most abundant component of Wutou decoction, which is widely used in China for rheumatoid arthritis. Benzoylmesaconine exhibits potent anti-inflammatory properties by inhibiting NF-kappaB. Benzoylmesaconine can suppress NLRP3 inflammasome activation by inhibiting IL-1beta secretion and GSDMD-N protein expression. Benzoylmesaconine reduces intracellular K+ efflux and disrupts NLRP3 inflammasome assembly[1][2][3].
Molecular Weight:
589.67
Purity:
99.56
CAS Number:
[63238-67-5]
Formula:
C31H43NO10
Target:
Interleukin Related,NF-kappaB
Application Notes:
MCE Product type: Natural Products
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