Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABAA receptor antagonist (IC50=2 µM). Bicuculline also blocks Ca2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice[1][2][3][4].
Molecular Weight:
367.35
Purity:
99.97
CAS Number:
[485-49-4]
Formula:
C20H17NO6
Target:
GABA Receptor
Application Notes:
MCE Product type: Natural Products
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