Curdione, CAS [[13657-68-6]]
Catalog Number:
MCE-HY-N0353
| Article Name: |
Curdione, CAS [[13657-68-6]] |
| Biozol Catalog Number: |
MCE-HY-N0353 |
| Supplier Catalog Number: |
HY-N0353 |
| Alternative Catalog Number: |
MCE-HY-N0353-10MMX1ML,MCE-HY-N0353-50MG,MCE-HY-N0353-100MG,MCE-HY-N0353-10MG,MCE-HY-N0353-5MG |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| Alternative Names: |
(+)-Curdione |
| Curdione ((+)-Curdione) is an orally active sesquiterpenoid. Curdione inhibits platelet aggregation. Curdione induces ferroptosis in colorectal cancer via m6A methylation mediated by METTL14 and YTHDF2. Curdione inhibits ferroptosis in Isoproterenol (HY-B0468)-induced myocardial infarction by regulating the Keap1/Trx1/GPX4 signaling pathway, suppressing oxidative stress (ROS) and apoptosis. Curdione ameliorates Doxorubicin (HY-15142)-induced cardiotoxicity by inhibiting oxidative stress (ROS) and activating the Nrf2/HO-1 pathway. Curdione ameliorates sepsis-induced lung injury by inhibiting platelet-mediated neutrophil extracellular trap formation. Curdione ameliorates Bleomycin (HY-17565A)-induced pulmonary fibrosis by inhibiting TGF-beta-induced fibroblast-to-myofibroblast differentiation. Curdione exhibits neuroprotective effects against focal cerebral ischemia-reperfusion injury in rats. Curdione exerts antiproliferative effects against human uterine leiomyosarcoma by targeting IDO1. Curdione protects vascular endothelial cells and atherosclerosis by regulating DNMT1-mediated ERBB4 promoter methylation. Curdione inhibits inducible prostaglandin E2 production (IC50 = 1.1 µM) and cyclooxygenase 2 expression[1][2][3][4][5][6][7][8][9][10][11][12]. |
| Molecular Weight: |
236.35 |
| Purity: |
99.92 |
| CAS Number: |
[13657-68-6] |
| Formula: |
C15H24O2 |
| Target: |
Apoptosis,Autophagy,Ferroptosis,Glutathione Peroxidase,Heme Oxygenase (HO),Indoleamine 2,3-Dioxygenase (IDO),Keap1-Nrf2,Reactive Oxygen Species (ROS),TGF-beta Receptor |
| Application Notes: |
MCE Product type: Natural Products |
