Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat[1][2][3].
Molecular Weight:
307.43
Purity:
99.93
CAS Number:
[19408-84-5]
Formula:
C18H29NO3
Target:
Akt,Apoptosis,Bcl-2 Family,Caspase,PI3K,Reactive Oxygen Species (ROS),TRP Channel
Application Notes:
MCE Product type: Natural Products
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