Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 µM, 0.61 µM, and 3.72µM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo[1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity[2].
Molecular Weight:
418.39
Purity:
99.99
CAS Number:
[551-15-5]
Formula:
C21H22O9
Target:
Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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