Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway [1].
Molecular Weight:
1091.24
Purity:
99.85
CAS Number:
[882664-74-6]
Formula:
C53H86O23
Target:
Akt,NF-kappaB,PI3K,Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Natural Products
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