Sesamoside is an orally active anti-inflammatory, anti-hypoxic and analgesic agent. Sesamoside inhibits the phosphorylation of ERK and JNK, downregulates NLRP3 expression, restricts the nuclear localization of P65, regulates AKR1B1 expression, and reduces the expression of TRPV1 gene in the spinal cord. Sesamoside reduces the production of TNF-alpha, IL-6, IL-1beta, iNOS and NO, restores cellular metabolism and organ function, and alleviates cold and mechanical hyperalgesia. Sesamoside can be used in research related to septic shock, high-altitude pulmonary edema and neuropathic pain[1][2][3][4].
Molecular Weight:
420.37
Purity:
99.77
CAS Number:
[117479-87-5]
Formula:
C17H24O12
Target:
Interleukin Related,JNK,PERK,TNF Receptor
Application Notes:
MCE Product type: Natural Products
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