Quercimeritrin (Quercetin-7-O-beta-D-glucopyranoside) is an orally active alpha-glucosidase inhibitor (with an IC50 of 79.88 µM against the Saccharomyces cerevisiae enzyme) and a P-gp substrate, with anti-angiogenic and antioxidant activities. Quercimeritrin does not cross the blood-brain barrier and does not inhibit cytochrome P450 enzymes. Quercimeritrin precisely binds to and inhibits the active sites of c-Kit, MMP-2, Aurora-A kinases and alpha-glucosidase, thereby disrupting target functions. Quercimeritrin effectively regulates postprandial blood glucose and also exhibits significant anti-angiogenic activity, which inhibits endothelial cell proliferation and microvascular growth. Quercimeritrin can be used in the research of diabetes and breast cancer[1][2][3].
Molecular Weight:
464.38
Purity:
99.48
CAS Number:
[491-50-9]
Formula:
C21H20O12
Target:
Aurora Kinase,c-Kit,Glycosidase,MMP,VEGFR
Application Notes:
MCE Product type: Natural Products
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