2-O-Galloylhyperin is an active natural compound with anti-inflammatory, antioxidant, anti-adipogenic, antifibrotic, and cytostatic activities. 2-O-Galloylhyperin upregulates SIRT1/Nrf2 signaling, inhibits NF-kappaB and MAPK (ERK1/2, p38, JNK) phosphorylation, suppresses TSHR activation, reduces ROS accumulation, and enhances SOD and GSH-Px activities. 2-O-Galloylhyperin protects against LPS-induced tissue injury, enhances survival, and inhibits adipogenesis and fibrosis. 2-O-Galloylhyperin can be used for the research of sepsis, acute lung injury, and thyroid eye disease[1][2][3][4].
Molecular Weight:
616.48
Purity:
99.57
CAS Number:
[53209-27-1]
Formula:
C28H24O16
Target:
ERK,JNK,Keap1-Nrf2,NF-kappaB,p38 MAPK,Reactive Oxygen Species (ROS),Sirtuin,SOD,TSH Receptor
Application Notes:
MCE Product type: Natural Products
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