Pentagalloylglucose (Penta-O-galloyl-beta-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3beta/beta-catenin pathway. Pentagalloylglucose inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities[1][2][3][4][5][6].
Molecular Weight:
940.68
Purity:
99.77
CAS Number:
[14937-32-7]
Formula:
C41H32O26
Target:
Apoptosis,E1/E2/E3 Enzyme,JAK,Keap1-Nrf2,Reactive Oxygen Species (ROS),beta-catenin
Application Notes:
MCE Product type: Natural Products
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