Vitexin-2-O-rhamnoside is an orally active flavonoid glycoside. Vitexin-2-O-rhamnoside inhibits Apoptosis, increases the phosphorylation levels of PI3K/Akt, inhibits caspase-3, SOD activity, and promotes cytokine (IL-2, IL-6, and IL-12) secretion. Vitexin-2-O-rhamnoside strongly inhibits DNA synthesis in MCF-7 cells with an IC50 of 17.5 µM. Vitexin-2-O-rhamnoside enhances immune function and improves the absorption of active compounds. Vitexin-2-O-rhamnoside has antioxidant activity. Vitexin-2-O-rhamnoside is used in the study of cardiovascular disease and immune-related diseases[1][2][3][4][5][6].
