Ginsenoside F3 is a saponin extracted from the leaves of Panax ginseng with immunoenhancing and antitumor immunostimulatory activities. Ginsenoside F3 upregulates RIPOR2 with a Kd value of 3.77 µM. Ginsenoside F3 enhances NF-kappaB activation, upregulates T-bet and downregulates GATA-3, increases the production of IL-2 and IFN-gamma, decreases the production of IL-4 and IL-10, reverses CD8 T-cell exhaustion, restores cytokine secretion, and enhances antitumor immunity in a mouse non-small cell lung cancer model. Ginsenoside F3 can be used for the research of non-small cell lung cancer[1][2].
Molecular Weight:
770.99
Purity:
99.84
CAS Number:
[62025-50-7]
Formula:
C41H70O13
Target:
IFNAR,Interleukin Related,NF-kappaB
Application Notes:
MCE Product type: Natural Products
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