Sanggenon C, a flavonoid, exerts protective effects against cardiac hypertrophy and fibrosis via suppression of the calcineurin/NFAT2 pathway. Sanggenon C inhibits mitochondrial fission to induce apoptosis by blocking the ERK signaling pathway. Sanggenon C inhibits inducible nitric oxide synthase expression in RAW264.7 cells, and TNF-alpha-stimulated cell adhesion and VCAM-1 expression, by suppressing NF-kappaB activity. Sanggenon C possesses antioxidant, anti-inflammatory and antitumor activities[1][2].
Molecular Weight:
708.71
Purity:
98.46
CAS Number:
[80651-76-9]
Formula:
C40H36O12
Target:
Apoptosis,ERK,NF-kappaB,Phosphatase
Application Notes:
MCE Product type: Natural Products
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