Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta[1]. Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models[2], has selective inhibitory activity towards cyclooxygenase-2 (COX-2)[1]. Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-B) and mitogen activated protein kinase (MAPK) signaling pathways[3].
Molecular Weight:
826.96
Purity:
99.89
CAS Number:
[65497-07-6]
Formula:
C42H66O16
Target:
COX,NF-kappaB
Application Notes:
MCE Product type: Natural Products
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