(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer and anti-inflammatory activity. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium[1][2][3].
Molecular Weight:
344.32
Purity:
99.63
CAS Number:
[7562-61-0]
Formula:
C18H16O7
Target:
Autophagy,Bacterial,mTOR
Application Notes:
MCE Product type: Natural Products
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