Usnic acid is a secondary metabolite of lichens with a unique dibenzofuran skeleton. Usnic acid inhibits DNA/RNA synthesis and has antibacterial activity. Usnic acid induces cell cycle arrest and apoptosis and has anticancer activity. Usnic acid inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Usnic acid has antioxidant and anti-inflammatory activities by inhibiting lipid peroxidation and myeloperoxidase[1][2][3][4].
Molecular Weight:
344.32
CAS Number:
[125-46-2]
Formula:
C18H16O7
Target:
Apoptosis,Bacterial,DNA/RNA Synthesis,Nuclear Factor of activated T Cells (NFAT)
Application Notes:
MCE Product type: Reference Standards
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