Eupalinolide A is a Yes-associated protein (YAP) degrader and HSP70 inducer. Eupalinolide A inhibits osteogenic differentiation of tendon-derived stem cells (TDSCs). Eupalinolide A induces autophagy in hepatocellular carcinoma cells via activating the ROS/ERK signaling pathway. Eupalinolide A protects PAM212 cells from UVB-, Menadione (HY-B0332)-, or heat shock-induced apoptosis. Eupalinolide A alleviates trauma-induced heterotopic ossification (HO) of Achilles tendon and inhibits growth of MHCC97-L and HCCLM3 hepatocellular carcinoma xenograft tumors in mice. Eupalinolide A can be used for the study of traumatic heterotopic ossification of tendons and hepatocellular carcinoma[1][2][3].
Molecular Weight:
462.49
Purity:
99.92
CAS Number:
[877822-40-7]
Formula:
C24H30O9
Target:
Apoptosis,Autophagy,DNA/RNA Synthesis,ERK,HSP,Reactive Oxygen Species (ROS),Tyrosinase,YAP
Application Notes:
MCE Product type: Natural Products
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