Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2].
Molecular Weight:
222.19
Purity:
99.94
CAS Number:
[486-21-5]
Formula:
C11H10O5
Target:
COX,ERK,MMP,Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Natural Products
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