Schisanhenol, a lignan, is an orally active antioxidant. Schisanhenol reduces AChE activity, increases SIRT1 and PGC-1alpha expression, and decreases phosphorylated Tau (Ser 396) levels. Schisanhenol increases SOD and glutathione peroxidase activity, decreases malondialdehyde (MDA) content, and inhibits UGT2B7 activitY. Schisanhenol attenuates ox-LDL-induced apoptosis, intracellular reactive oxygen species generation, and cytotoxicity in endothelial cells. Schisanhenol inhibits LDL oxidation, brain mitochondrial and membrane peroxidative damage, and brain mitochondrial swelling and disintegration. Schisanhenol can be used for the research of Alzheimers disease, atherosclerosis, brain ischemia, and age-related brain deterioration[1][2][3][4].
Molecular Weight:
402.48
Purity:
99.99
CAS Number:
[69363-14-0]
Formula:
C23H30O6
Target:
Cholinesterase (ChE),Sirtuin,SOD,Tau Protein,UGT
Application Notes:
MCE Product type: Natural Products
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