Ginsenoside Rg5 is the main component of Red ginseng and IGF-1R agonist. Ginsenoside Rg5 compets for the binding site of IGF-1R and blocks the binding of IGF-1 to IGF-1R (IC50 about 90 nM). Ginsenoside Rg5 also inhibits the mRNA expression of COX-2 via suppression of the DNA binding activities of NF-kappaB p65.
Molecular Weight:
767.00
Purity:
99.88
CAS Number:
[186763-78-0]
Formula:
C42H70O12
Target:
COX,IGF-1R,NF-kappaB
Application Notes:
MCE Product type: Natural Products
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