()-Stylopine (Tetrahydrocoptisine) is an alkaloid compound. ()-Stylopine can be isolated from the tubers of the plant Corydalis. ()-Stylopine inhibits TNF-alpha, IL-6, and NO production, and attenuates phosphorylation of p38 MAPK, ERK1/2. ()-Stylopine inhibits NF-kappaB expression. ()-Stylopine exhibits anti-inflammatory activity. ()-Stylopine has protective effects against foot edema, gastric ulcers, anxiety, depression, and acute lung injury[1][2][3][4].
