Columbamine (Columbamin, Dehydroisocorypalmine) is an organic heterotetracyclic alkaloid extracted from plants. Columbamine is a metabolite of Berberine (HY-N0716). Columbamine inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 30.6 µM). Columbamine induces apoptosis in cancer cells. Columbamine can be used for antioxidant, anti-inflammatory, antitumor, antifungal, antiparasite, hepatoprotective, neuroprotective, hypolipidemic and hypoglycemic study[1][2][3][4][5].
Molecular Weight:
338.38
Purity:
99.70
CAS Number:
[3621-36-1]
Formula:
C20H20NO4
Target:
Apoptosis,Cytochrome P450,Parasite
Application Notes:
MCE Product type: Natural Products
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