Phlorofucofuroeckol A is a FcepsilonRI inhibitor with low cytotoxicity toward basophilic leukemia cells. Phlorofucofuroeckol A suppresses binding activity between IgE and FcepsilonRI receptor. Phlorofucofuroeckol A inhibits histamine release from basophilic leukemia cells stimulated by IgE/anti-IgE or calcium ionophore A23187 (HY-N6687). Phlorofucofuroeckol A inhibits beta-hexosaminidase release from basophilic leukemia cells stimulated by IgE/DNP-BSA. Phlorofucofuroeckol A can be used for the research of allergy disease[1].
Molecular Weight:
602.46
CAS Number:
[128129-56-6]
Formula:
C30H18O14
Target:
Fc Receptor (FcR)
Application Notes:
MCE Product type: Natural Products
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