Tamarixetin (4-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC50 of 49.73 µM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways[1][2][3][4].
Molecular Weight:
316.26
Purity:
98.80
CAS Number:
[603-61-2]
Formula:
C16H12O7
Target:
Akt,Apoptosis,Bacterial,ClpP,COX,Endogenous Metabolite,Interleukin Related,JNK,p38 MAPK,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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