Feralolide is a dihydroisocoumarin isolated from the methanolic extract of aloe vera resin. Feralolide is also a dual inhibitor of AChE and BuChE, with IC50s of 55 µg/mL and 52 µg/mL respectively. Feralolide has antioxidant activity and inhibits 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2'-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS). Feralolide could be used in research into cognitive disorders such as Alzheimers disease, potentially restoring and enhancing memory[1].
Molecular Weight:
344.32
CAS Number:
[149418-38-2]
Formula:
C18H16O7
Target:
Cholinesterase (ChE)
Application Notes:
MCE Product type: Natural Products
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