Ginkgo biloba extract is a natural product that can be isolated from Ginkgo biloba leaves. Ginkgo biloba extract alleviates oxidative stress-induced neuronal apoptosis (Apoptosis) by stabilizing mitochondrial function, regulating Bcl-2 family proteins and inhibiting caspase activation. Ginkgo biloba extract alleviates testicular injury by upregulating SKP2 and inhibiting Beclin1-independent autophagy (Autophagy). Ginkgo biloba extract alleviates various types of neuronal damage in animal models. Ginkgo biloba extract reduces behavioral sensitization in rats. Ginkgo biloba extract counteracts Abeta-induced neurotoxicity by blocking a series of Abeta-triggered events, including glucose uptake, ROS accumulation, AKT activation, mitochondrial dysfunction, JNK and ERK 1/2 pathways, and apoptosis, and also interferes with the formation of Abeta oligomers. Ginkgo biloba extract is applicable to research related to cerebral hypoperfusion, testicular injury, Alzheimers disease, Parkinsons disease, multi-infarct dementia, stroke, traumatic brain injury and amyotrophic lateral sclerosis[1][2].
CAS Number:
[90045-36-6]
Target:
Akt,Apoptosis,Autophagy,Bcl-2 Family,Caspase,ERK,JNK,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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