Antimycin A2 is a selective inhibitor of the cytochrome b-c1 complex in the mitochondrial electron transport chain. Antimycin A2 disrupts mitochondrial membrane potential and produces reactive oxygen species (ROS) by inhibiting electron transfer between cytochrome b and c. Antimycin A2 has bactericidal and piscicidal activity, as well as tumor cell growth inhibitory effects, and can induce S-phase cell cycle arrest and apoptosis in HeLa cells. Antimycin A2 is suitable for research of cervical cancer and fisheries management. Antimycin A2 can be naturally isolated from the fermentation products of Streptomyces sp. strains[1].
Molecular Weight:
534.60
Purity:
99
CAS Number:
[27220-57-1]
Formula:
C27H38N2O9
Target:
Apoptosis,Cytochrome P450,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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