Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 µg/mL.
Molecular Weight:
749.97
Purity:
96.6
CAS Number:
[33538-71-5]
Formula:
C41H67NO11
Target:
Antibiotic,ATP Synthase
Application Notes:
MCE Product type: Natural Products
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