Seneciphylline is an orally effective hepatotoxic inducer. Seneciphylline is metabolized by CYP450 enzymes into active intermediates, which covalently bind to intracellular biomacromolecules such as proteins and DNA to form adducts, which in turn trigger a series of toxic reactions, such as inducing cell apoptosis and damaging mitochondrial function. Seneciphylline can be used in hepatotoxicity research[1][2].
Molecular Weight:
333.38
Purity:
99.93
CAS Number:
[480-81-9]
Formula:
C18H23NO5
Target:
Cytochrome P450,Glutathione S-transferase
Application Notes:
MCE Product type: Natural Products
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