12-Deoxyphorbol 13-palmitate is a traditional Chinese medicine monomer with antitumor activity that can be isolated from the root of Euphorbia fischeriana. 12-Deoxyphorbol 13-palmitate induces gastric cancer cell cycle arrest and apoptosis by regulating key cell cycle regulators such as cyclin B,cyclin A and CDC2. In addition, 12-Deoxyphorbol 13-palmitate can significantly weaken APOL2-SERCA2-PERK-HES1 signaling and slow liver fibrosis by targeting APOL2[1][2].
Molecular Weight:
586.84
Purity:
99.85
CAS Number:
[66583-59-3]
Formula:
C36H58O6
Target:
Apoptosis,CDK
Application Notes:
MCE Product type: Natural Products
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