Cernuumolide J, CAS [[2019163-02-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N13294
Supplier Catalog Number:
HY-N13294
Alternative Catalog Number:
MCE-HY-N13294-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
TMJ-105
Cernuumolide J (TMJ-105) is an JAK2/STAT3 inhibitor. Cernuumolide J induces G2/M phase arrest and apoptosis in HEL leukemia cells by downregulating the phosphorylation of JAK2, STAT3, and Erk, and activating the phosphorylation of JNK and p38 MAPK. Cernuumolide J inhibits HEL leukemia cell growth in a time- and concentration-dependent manner, with an IC50 value of 1.79 µM. Cernuumolide J can be used for research in the field of anti-cancer therapy[1].
Molecular Weight:
450.52
CAS Number:
[2019163-02-9]
Formula:
C24H34O8
Target:
Apoptosis,ERK,JAK,JNK,p38 MAPK,STAT
Application Notes:
MCE Product type: Natural Products
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