Roseoside is an inhibitor of DNA gyrase and HAV 3C protease, and also inhibits HCV NS5A/B replicase in human systems with an IC50 of 20 µM. Roseoside binds to the active site of enzymes and stabilizes the interaction by forming hydrogen bonds with key amino acid residues. Roseoside inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, and Candida albicans, and interferes with HCV RNA replication in vitro by inhibiting HCV NS5A/B replicase (IC50=20 µM). Roseoside shows no cytotoxicity and serves as a research tool for studies related to bacterial infections, candidiasis, HAV and HCV[1][2].
Molecular Weight:
386.44
Purity:
96.99
CAS Number:
[54835-70-0]
Formula:
C19H30O8
Target:
Bacterial,DNA/RNA Synthesis,HCV,HCV Protease
Application Notes:
MCE Product type: Natural Products
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