Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active constituent in Artemisia argyi leaves. Isoscopoletin shows substantial inhibition against cell proliferation, with IC50s of 4.0 µM and 1.6 µM for human CCRF-CEM leukaemia cells and multidrug resistant subline CEM/ADR5000, respectively[1]. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) possesses inhibitory activity against HBV replication[2]. Isoscopoletin exhibits anti-inflammatory activity through inhibition of MAPK/NF-kappaB/STAT/AKT signaling pathway[3].
Molecular Weight:
192.17
Purity:
99.92
CAS Number:
[776-86-3]
Formula:
C10H8O4
Target:
Akt,ERK,HBV,JNK,NF-kappaB,p38 MAPK,STAT
Application Notes:
MCE Product type: Natural Products
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