Argyrin B, a natural product cyclic peptide, is a reversible, non-competitive immunoproteasome inhibitor. Argyrin B shows selective inhibition of the beta5i and beta1i sites of the immunoproteasome over the beta5c and beta1c sites of the constitutive proteasome with nearly 20-fold selective inhibition of beta1i over the homologous beta1c. Argyrin B has antibacterial effects[1].
Molecular Weight:
838.93
CAS Number:
[174423-36-0]
Formula:
C41H46N10O8S
Target:
Bacterial,Proteasome
Application Notes:
MCE Product type: Natural Products
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