Aspulvinone H, CAS [[57744-69-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N14093
Supplier Catalog Number:
HY-N14093
Alternative Catalog Number:
MCE-HY-N14093-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Aspulvinone H is an orally active inhibitor of AChE, pancreatic lipase, glutamic-oxaloacetic transaminase 1, and alpha-glucosidase, with IC50 values of 25.95 µM, 47.06 µM, 5.91/6.91 µM, and 4.6 µM, respectively. It has a Ka of 2.14 µM against GOT1 and a Ki of 6.58 µM against alpha-glucosidase. Aspulvinone H inhibits cancer cell proliferation, interferes with glutamine metabolism, elevates ROS levels, and induces cell apoptosis and S-phase arrest. Aspulvinone H exhibits antibacterial activity against Staphylococcus aureus. Aspulvinone H inhibits the growth of pancreatic ductal adenocarcinoma xenografts. Aspulvinone H reduces postprandial blood glucose in mice. Aspulvinone H can be used in research related to pancreatic ductal adenocarcinoma, diabetes, and Staphylococcus aureus infection[1][2][3][4].
Molecular Weight:
432.51
CAS Number:
[57744-69-1]
Formula:
C27H28O5
Target:
Apoptosis,Bacterial,Cholinesterase (ChE),Lipase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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