Gabaculine is an amino acid neurotoxin and blood-brain barrier-permeable GABA transaminase inhibitor, with an IC50 of 1 µM in beef and Pseudomonas ovalis. Gabaculine elevates endogenous synaptic and brain GABA levels and enhances GABA activity. Gabaculine induces sedation, hypothermia, loss of righting reflex, and prevents convulsions in mice. Gabaculine is applicable to research related to neurological disorders[1][2][3].
Molecular Weight:
139.15
CAS Number:
[59556-18-2]
Formula:
C7H9NO2
Target:
GABA Receptor
Application Notes:
MCE Product type: Natural Products
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