Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells[1]. Ganoderic acid D induces HeLa human cervical carcinoma apoptosis[2].
Molecular Weight:
514.65
Purity:
99.89
CAS Number:
[108340-60-9]
Formula:
C30H42O7
Target:
Apoptosis,Sirtuin
Application Notes:
MCE Product type: Natural Products
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